PHARMACOLOGICAL RESEARCH文献大全第14页

Differential effects of central and peripheral cholinergic blockade on water consumption by rats.
abstract：:Atropine (5 mg/kg, s.c., twice daily) had no significant effect on 24-h water consumption on day 1 of treatment; on subsequent days the rats showed a significant increase. Procyclidine (5 mg/kg, s.c., twice daily) had a similar effect, except that the increase in daily water consumption began on the third day of treat...

journal_title：Pharmacological research

pub_type： 杂志文章

doi：10.1016/1043-6618(90)90745-y

authors： Alharbi MM,Maickel RP

更新日期：1990-01-01 00:00:00
Diet-induced reduction in serum lipoproteins stimulates cell proliferation in weanling rats.
abstract：:Male weanling Wistar rats were fed a 4% cholestyramine diet and used as a model to demonstrate that a reduction in serum low density lipoproteins stimulates de novo cholesterogenesis leading to DNA synthesis and cell proliferation. Feeding this diet resulted in a decrease in serum very low density lipoproteins and low...

journal_title：Pharmacological research

pub_type： 杂志文章

doi：10.1016/1043-6618(89)90195-3

authors： Kazanecki ME,Melhem MF,Spichty KJ,Kelly RH,Rao KN

更新日期：1989-09-01 00:00:00
Antimalarial efficacy of arteether against multiple drug resistant strain of Plasmodium yoelii nigeriensis.
abstract：:New quick-acting blood schizontocides are needed to contain the spread of multiple drug resistant strains of P. falciparum and for the treatment of the cerebral malaria cases. A multiple drug resistant strain of P. yoelii nigeriensis resistant to mefloquine (128 mg/kg x 6 days), quinine (300 mg/kg x 7 days) and chloro...

journal_title：Pharmacological research

pub_type： 杂志文章

doi：10.1016/1043-6618(89)90159-x

authors： Dutta GP,Bajpai R,Vishwakarma RA

更新日期：1989-07-01 00:00:00
Influence of PLA2-PG system on purine release and cAMP content in dissociated primary glial cultures from rat striatum.
abstract：:Purine release and prostaglandin (PG) outflow were simultaneously evaluated from untreated glial primary cultures of rat striatum, at rest and under field electrical stimulation. Purine release was also assayed from sister cultured cells in which a suitable pharmacological treatment with 1 x 10(-6) M dexamethasone or ...

journal_title：Pharmacological research

pub_type： 杂志文章

doi：10.1016/s1043-6618(89)80005-2

authors： Caciagli F,Ciccarelli R,Di Iorio P,Tacconelli L,Ballerini P

更新日期：1989-05-01 00:00:00
Bezafibrate inhibits HMG-CoA reductase activity in incubated blood mononuclear cells from normal subjects and patients with heterozygous familial hypercholesterolaemia.
abstract：:In incubated blood mononuclear cells from normal subjects bezafibrate inhibited the incorporation of 14C-acetate into squalene, methylsterols and cholesterol. Similarly, the drug produced a sharp decrease of the incorporation of labelled 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) into non-saponifiable lipids, whi...

journal_title：Pharmacological research

pub_type： 杂志文章

doi：10.1016/s1043-6618(89)80002-7

authors： Blasi F,Sommariva D,Cosentini R,Cavaiani B,Fasoli A

更新日期：1989-05-01 00:00:00
Newer agents for coronary thrombolysis. Perspectives from clinical studies.
abstract：:Myocardial infarction (MI) is a major cause of morbidity and mortality in western countries and the formation of intracoronary thrombi is recognized as a critical determinant of this ischaemic event. Since streptokinase and urokinase cause in vitro lysis of clots, it was though that these drugs were also effective in ...

journal_title：Pharmacological research

pub_type： 杂志文章,评审

doi：10.1016/1043-6618(89)90233-8

authors： Di Minno G,Margaglione M,Cerbone AM,Papa R,Mattei A

更新日期：1989-03-01 00:00:00

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